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#🎗️विश्व कैंसर दिवस🎗️
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![🎗️विश्व कैंसर दिवस🎗️ - Presented by J.S.KMCLASSES CANCER ONE PAGE REVISION (NEET ) Defition Cell Cycle Link Loss of control at GIIS checkpoint Uncontrolled cell division due to regulation loss of cell cycle Mutation in regulatory genes Leads to tumor formation Failure of apoptosis Cells become immortal Carcinogens Cell Cycle Link Physical UV rays, Xrays L Loss of control at GI/S checkpoint Chemical - Tobacco, asbestos; Mutation in regulatory genes benzene Failure of apoptosis Biological HPV, HBV, EBV Cancer Genes Hallmarksof Cancer Oncogenes] Self-sufficient growth signals Evade apoptosis Mutated proto-oncogenes Unlimited replication Promote division Angiogenesis Example: RAS Metastasis Tumor Suppressor Genes] Stop Tumor Types division normally Loss cancer Malignant Benign ? Example: p53 (Guardian of Genome) Invasivel Metastatic Rapid growth Invasive Halmarks of Cancer Treatment Self-sufficient growth signals Evade apoptosis Chemotherapy Surgery Radiotherapy Unlimited replication Immunotherap Targeted therapy Angiogenesis Metastasis NEET HOT POINTS Guardian of genomel Tobacco major cause Tobacco p53= HPV vaccination Tumor suppressor genes loss of function F ALL IHE BESII Presented by J.S.KMCLASSES CANCER ONE PAGE REVISION (NEET ) Defition Cell Cycle Link Loss of control at GIIS checkpoint Uncontrolled cell division due to regulation loss of cell cycle Mutation in regulatory genes Leads to tumor formation Failure of apoptosis Cells become immortal Carcinogens Cell Cycle Link Physical UV rays, Xrays L Loss of control at GI/S checkpoint Chemical - Tobacco, asbestos; Mutation in regulatory genes benzene Failure of apoptosis Biological HPV, HBV, EBV Cancer Genes Hallmarksof Cancer Oncogenes] Self-sufficient growth signals Evade apoptosis Mutated proto-oncogenes Unlimited replication Promote division Angiogenesis Example: RAS Metastasis Tumor Suppressor Genes] Stop Tumor Types division normally Loss cancer Malignant Benign ? Example: p53 (Guardian of Genome) Invasivel Metastatic Rapid growth Invasive Halmarks of Cancer Treatment Self-sufficient growth signals Evade apoptosis Chemotherapy Surgery Radiotherapy Unlimited replication Immunotherap Targeted therapy Angiogenesis Metastasis NEET HOT POINTS Guardian of genomel Tobacco major cause Tobacco p53= HPV vaccination Tumor suppressor genes loss of function F ALL IHE BESII - ShareChat](https://cdn4.sharechat.com/bd5223f_s1w/compressed_gm_40_img_807738_71e370a_1770179806149_sc.jpg?tenant=sc&referrer=pwa-sharechat-service&f=149_sc.jpg "🎗️विश्व कैंसर दिवस🎗️ - Presented by J.S.KMCLASSES CANCER ONE PAGE REVISION (NEET ) Defition Cell Cycle Link Loss of control at GIIS checkpoint Uncontrolled cell division due to regulation loss of cell cycle Mutation in regulatory genes Leads to tumor formation Failure of apoptosis Cells become immortal Carcinogens Cell Cycle Link Physical UV rays, Xrays L Loss of control at GI/S checkpoint Chemical - Tobacco, asbestos; Mutation in regulatory genes benzene Failure of apoptosis Biological HPV, HBV, EBV Cancer Genes Hallmarksof Cancer Oncogenes] Self-sufficient growth signals Evade apoptosis Mutated proto-oncogenes Unlimited replication Promote division Angiogenesis Example: RAS Metastasis Tumor Suppressor Genes] Stop Tumor Types division normally Loss cancer Malignant Benign ? Example: p53 (Guardian of Genome) Invasivel Metastatic Rapid growth Invasive Halmarks of Cancer Treatment Self-sufficient growth signals Evade apoptosis Chemotherapy Surgery Radiotherapy Unlimited replication Immunotherap Targeted therapy Angiogenesis Metastasis NEET HOT POINTS Guardian of genomel Tobacco major cause Tobacco p53= HPV vaccination Tumor suppressor genes loss of function F ALL IHE BESII Presented by J.S.KMCLASSES CANCER ONE PAGE REVISION (NEET ) Defition Cell Cycle Link Loss of control at GIIS checkpoint Uncontrolled cell division due to regulation loss of cell cycle Mutation in regulatory genes Leads to tumor formation Failure of apoptosis Cells become immortal Carcinogens Cell Cycle Link Physical UV rays, Xrays L Loss of control at GI/S checkpoint Chemical - Tobacco, asbestos; Mutation in regulatory genes benzene Failure of apoptosis Biological HPV, HBV, EBV Cancer Genes Hallmarksof Cancer Oncogenes] Self-sufficient growth signals Evade apoptosis Mutated proto-oncogenes Unlimited replication Promote division Angiogenesis Example: RAS Metastasis Tumor Suppressor Genes] Stop Tumor Types division normally Loss cancer Malignant Benign ? Example: p53 (Guardian of Genome) Invasivel Metastatic Rapid growth Invasive Halmarks of Cancer Treatment Self-sufficient growth signals Evade apoptosis Chemotherapy Surgery Radiotherapy Unlimited replication Immunotherap Targeted therapy Angiogenesis Metastasis NEET HOT POINTS Guardian of genomel Tobacco major cause Tobacco p53= HPV vaccination Tumor suppressor genes loss of function F ALL IHE BESII - ShareChat")