Sinus Pain vs Migraine Know the Difference! Sinus pain and can feel similar, but they come from very different causes. Understanding the difference helps you choose the right treatment and get faster relief. If your “sinus headache” keeps coming back without infection or thick mucus, it may actually be a migraine. Knowing your symptoms is the first step to feeling better. Save this for later! #MigraineAwareness #migrainetips #sinusheadache #migrainesupport #migraine